Vasopressors for Septic Shock

  • Epinephrine and norepinephrine are both acceptable, evidence-based approaches to hemodynamic support in septic shock.
  • Individual patient responsiveness to vasopressors is variable and unpredictable.
  • Some patients respond better to epinephrine than norepinephrine.
  • For patients who are not responding well to norepinephrine, it is reasonable to empirically trial a low dose of epinephrine (“epinephrine challenge”).

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EMKF

The Emergency Medicine Kenya (EMK) Foundation is a not-for-profit organization registered in Kenya in 2015 that aims to ensure timely, accessible and quality lifesaving emergency care in Kenya.