Thyroid disorders exist on a spectrum from myxedema coma to thyroid storm, with a large area in between.
Hyperthyroidism – too much thyroid hormones only from the thyroid gland Thyrotoxicosis – too much thyroid hormone from any cause (i.e. taking too much thyroid supplement) Thyroid Storm – see above. Thyrotoxicosis with increased adrenergic hyperactivity or abnormal response to the thyroid hormones by the peripheral tissues Myxedema coma – These patients are the opposite […]
Management of thyroid storm entails searching for and treating that precipitating factor most commonly subtherapeutic antithyroid medication or infection. Empiric use of antibiotics is not recommended, along with pharmacologic therapy with the 3 Ps and 2 Ss; Propylthiouracil (PTU) or Methimazole to reduce thyroid hormone synthesis and also assist propranolol in decreasing peripheral conversion of […]