Sodium bicarbonate therapy in DKA (or any other acidosis for that matter) is associated with risks that outweigh NO BENEFITS…DO NO HARM!!!
- Neither a recent systematic review nor the largest single retrospective cohort of severe DKA support routine use of bicarbonate therapy in DKA
- Bicarbonate is associated with risk of cerebral oedema and prolonged hospitalisation in paediatric DKA
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