Induction Agents
| Medication | Weight-Based Dosing | Time to Onset of Action | Adverse Effects/
Contraindications |
| Etomidate | 0.3 mg/kg | <1 minute | May cause clinically insignificant adrenal suppression. |
| Ketamine | 1-2 mg/kg | 1-3 minutes | May increase blood pressure. May cause hypersalivation. |
| Propofol | 2 mg/kg | <1 minute | May cause hypotension. Cardiac depressant. Contraindicated in egg/soybean allergy |
| Midazolam | 0.3 mg/kg | 1-5 minutes | May cause hypotension |
Paralytics
| Medication | Weight-Based Dosing | Time to Onset of Action | Adverse Effects/
Contraindications |
| Succinylcholine | 1.5 – 2.0 mg/kg | 45-60 seconds | Bradycardia. Malignant hyperthermia. Hyperkalemia. |
| Rocuronium | 1.2 mg/kg | 45-60 seconds | |
| Vecuronium | 0.1 mg/kg | 2-4 minutes | Questionable RSI utility when rocuronium available |
Post-Intubation Sedation
| Medication | Weight-Based Dosing | Notes |
| Midazolam | 0.04-0.2 mg/kg/hr | Short duration, but with long-term use has long half-life. Often used with fentanyl |
| Propofol | 5-80 mcg/kg/min | Propofol Infusion Syndrome with long term use: monitor TG, amylase/lipase |
| Dexmedetomidine | 0.2-0.7 mcg/kg/hr | |
| Ketamine | 0.5-1 mg/kg/hr | May decrease bronchospasm |
| Fentanyl | 1-2 mcg/kg bolus25-250 mcg/hr | |
