Management of a massive GI bleed

For known upper GI bleed, give PPI as soon as access is obtained – it makes endoscopy easier. Decreasing the acidity provides benefit acutely by improving platelet function, and in the long run by adding mucosal protection. Start with an 80 mg bolus followed by 8 mg/hr of Esomeprazole or Pantoprazole.

Emergency Medicine Kenya Foundation