- Classically, herpes zoster will present with rash and pain in a dermatomal distribution
- Immunocompromised patients are at greater risk for significant complications of zoster, including visceral dissemination and zoster ophthalmicus
- Appropriate therapy includes antiviral therapy within 72 hours of onset of symptoms and analgesia for acute neuritis
- Disseminated zoster and zoster ophthalmicus threatening sight should be treated with IV antivirals