An exacerbation of COPD is defined as an event characterized by dyspnea and/or cough and sputum that worsen over < 14 days. Exacerbations of COPD are often associated with increased local and systemic inflammation caused by airway infection, pollution, or other insults to the lungs.
Clinical Guidelines
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Rabies vaccines and immunoglobulins: WHO position
PEP consists of the following steps:
- All bite wounds and scratches should be attended to as soon as possible after the exposure; thorough washing and flushing of the wound for approximately 15 minutes, with soap or detergent and copious
amounts of water, is required. Where available, an iodine-containing, or similarly viricidal, topical
preparation should be applied to the wound. - RIG should be administered for severe category III exposures. Wounds that require suturing should be
sutured loosely and only after RIG infiltration into the wound. - A series of rabies vaccine injections should be administered promptly after an exposure.
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