Centor Criteria: Antibiotics or Not?

 

The Centor score is an appropriate screening method for acute tonsillitis but limited to patients of at least 15 years of age. The Centor score uses 4 signs and symptoms and a scale of 0 to 4 for diagnosis.

  1. history of fever > 38oC,
  2. absence of a cough,
  3. swollen and tender anterior cervical lymph nodes, and
  4. tonsillar exudates or swelling

Both the sensitivity and specificity of this prediction rule are 75%, compared with throat cultures. Antibiotics are advised if the Centor score is 3 or above.

 

Chest Pain in Atrial Fibrillation

This is a great example of how the dichotomy between STEMI and Non-STEMI is false.  They are both due to thrombus in the coronary artery and both are very dangerous.  STEMI and NonSTEMI exist on a spectrum.  Thrombus can lyse and propagate, and NonSTEMI can convert to STEMI.

 

UTI Myths and Misconceptions

  • UTI is a clinical diagnosis, not a laboratory one. Dysuria plus urinary frequency in the absence of symptoms of STI is diagnostic.
  • Most patients with a clinical picture consistent with a lower UTI do not require urine tests.
  • The indications for urine tests for suspected lower UTI include immunocompromised patients, history of multiple courses of antimicrobial therapy, history of antibiotic resistance and history of multiple drug allergies.
  • While bacteria seen on microscopy is predictive of a positive culture, it is not necessarily diagnostic of a UTI as the positive culture could represent a contaminant or asymptomatic bacteriuria.
  • A common pitfall is treating non-pregnant patients with asymptomatic bacteriuria with antibiotics. Asymptomatic bacteriuria is very common in all age groups and is often misdiagnosed as a UTI.
  • Do not routinely treat catheterized patients found to have pyuria or candida in their urine.
  • A common pitfall is to assume that the cause of altered level of awareness in an elderly is a UTI upon finding pyuria or bacteriuria on urinalysis leading to premature closure and missing a more serious diagnosis.
  • Imaging is not routinely required for patients suspected clinically of pyelonephritis.
  • Cranberry juice, direction of wiping and voiding post intercourse are not effective in preventing recurrent UTIs
  • 3-5 days duration of therapy is sufficient for the vast majority of lower UTI